BDBM50380144 CHEMBL2010994::carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 8
SMILES CC(C)(C)c1cc(=O)[nH]c(SCC(=O)c2ccc(cc2)S(N)(=O)=O)n1
InChI Key InChIKey=OMYTZYUGUKDESE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 20 hits for monomerid = 50380144
Affinity DataKoff: 3.30E+6s-1pH: 8.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as association rate constant at pH 8 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKoff: 2.50E+6s-1Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as association rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKoff: 4.00E+5s-1pH: 6.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as association rate constant at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKoff: 3.10E+6s-1pH: 7.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as association rate constant at pH 7 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 13nMpH: 8.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from kinetic parameters at pH 8 by surface pl...More data for this Ligand-Target Pair
Affinity DataKd: 20nMpH: 8.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from saturation signal at pH 8 by surface pla...More data for this Ligand-Target Pair
Affinity DataKon: 0.150M-1s-1pH: 6.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation rate constant at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 360nMpH: 6.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from kinetic parameters at pH 6 by surface pl...More data for this Ligand-Target Pair
Affinity DataKd: 440nMpH: 6.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from saturation signal at pH 6 by surface pla...More data for this Ligand-Target Pair
Affinity DataKon: 0.140M-1s-1pH: 7.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation rate constant at pH 7 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 46nMpH: 7.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from kinetic parameters at pH 7 by surface pl...More data for this Ligand-Target Pair
Affinity DataKd: 56nMpH: 7.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from saturation signal at pH 7 by surface pla...More data for this Ligand-Target Pair
Affinity DataKon: 0.0400M-1s-1pH: 8.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation rate constant at pH 8 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKon: 0.0840M-1s-1Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 33nMAssay Description:Binding affinity to human recombinant CA9 catalytic domain after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Binding affinity to human recombinant CA9 catalytic domain by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKon: 0.0740M-1s-1Assay Description:Binding affinity to human CA9 catalytic domain expressed in mammalian expression system assessed as dissociation rate constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 42nMAssay Description:Binding affinity to human CA9 catalytic domain expressed in mammalian expression system assessed as thermodynamic equilibrium constant at pH 7 by SPR...More data for this Ligand-Target Pair
Affinity DataKon: 0.0740M-1s-1Assay Description:Binding affinity to human CA9 catalytic domain expressed in mammalian expression system assessed as intrinsic dissociation rate constant at pH 7 by S...More data for this Ligand-Target Pair
Affinity DataKd: 0.0800nMAssay Description:Binding affinity to human CA9 catalytic domain expressed in mammalian expression system assessed as intrinsic thermodynamic equilibrium constant at p...More data for this Ligand-Target Pair